{"id":295,"date":"2019-08-27T12:41:42","date_gmt":"2019-08-27T11:41:42","guid":{"rendered":"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/?page_id=295"},"modified":"2025-12-15T12:22:25","modified_gmt":"2025-12-15T12:22:25","slug":"previous-symposia","status":"publish","type":"page","link":"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/previous-symposia\/","title":{"rendered":"Previous Symposia"},"content":{"rendered":"\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Gallery<\/summary><style type=\"text\/css\">\n#foogallery-gallery-1206 .fg-image { width: 333px; }\n#foogallery-gallery-1206 { --fg-gutter: 5px; }<\/style>\n\t\t\t<div class=\"foogallery foogallery-container foogallery-default foogallery-lightbox-foogallery fg-center fg-m-col3 fg-default fg-ready fg-light fg-border-thin fg-shadow-outline fg-loading-default fg-loaded-fade-in fg-caption-always fg-hover-fade fg-transparent-overlays fg-c-c\" id=\"foogallery-gallery-1206\" data-foogallery=\"{&quot;item&quot;:{&quot;showCaptionTitle&quot;:true,&quot;showCaptionDescription&quot;:true},&quot;lazy&quot;:true}\" data-foogallery-lightbox=\"{&quot;thumbs&quot;:&quot;bottom&quot;,&quot;thumbsCaptions&quot;:false,&quot;thumbsBestFit&quot;:false,&quot;thumbsSmall&quot;:false,&quot;thumbsCaptionsAlign&quot;:&quot;default&quot;,&quot;info&quot;:&quot;bottom&quot;,&quot;infoVisible&quot;:true,&quot;infoOverlay&quot;:true,&quot;infoAlign&quot;:&quot;default&quot;,&quot;transition&quot;:&quot;fade&quot;,&quot;hoverButtons&quot;:false,&quot;fitMedia&quot;:false,&quot;noScrollbars&quot;:true,&quot;preserveButtonSpace&quot;:true,&quot;buttons&quot;:{&quot;fullscreen&quot;:true,&quot;info&quot;:true,&quot;thumbs&quot;:false},&quot;video&quot;:{&quot;autoPlay&quot;:true}}\" style=\"--fg-title-line-clamp: 0; --fg-description-line-clamp: 0;\" >\n\t<div class=\"fg-item fg-type-image fg-idle\"><figure class=\"fg-item-inner\"><a href=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/Next-Gen-Biophys-2017.jpg\" data-caption-title=\"NGBS organizers 2017\" data-attachment-id=\"1199\" data-type=\"image\" class=\"fg-thumb\"><span class=\"fg-image-wrap\"><img fetchpriority=\"high\" decoding=\"async\" title=\"NGBS organizers 2017\" width=\"333\" height=\"200\" class=\"skip-lazy fg-image\" data-src-fg=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/cache\/Next-Gen-Biophys-2017\/1054176975.jpg\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20width%3D%22333%22%20height%3D%22200%22%20viewBox%3D%220%200%20333%20200%22%3E%3C%2Fsvg%3E\" loading=\"eager\"><\/span><span class=\"fg-image-overlay\"><\/span><\/a><figcaption class=\"fg-caption\"><div class=\"fg-caption-inner\"><div class=\"fg-caption-title\">NGBS organizers 2017<\/div><\/div><\/figcaption><\/figure><div class=\"fg-loader\"><\/div><\/div><div class=\"fg-item fg-type-image fg-idle\"><figure class=\"fg-item-inner\"><a href=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/NGBS-organizers-2018-1-scaled.jpg\" data-caption-title=\"NGBS organizers 2018\" data-attachment-id=\"1190\" data-type=\"image\" class=\"fg-thumb\"><span class=\"fg-image-wrap\"><img decoding=\"async\" title=\"NGBS organizers 2018\" width=\"333\" height=\"200\" class=\"skip-lazy fg-image\" data-src-fg=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/cache\/NGBS-organizers-2018-1-scaled\/2176883357.jpg\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20width%3D%22333%22%20height%3D%22200%22%20viewBox%3D%220%200%20333%20200%22%3E%3C%2Fsvg%3E\" loading=\"eager\"><\/span><span class=\"fg-image-overlay\"><\/span><\/a><figcaption class=\"fg-caption\"><div class=\"fg-caption-inner\"><div class=\"fg-caption-title\">NGBS organizers 2018<\/div><\/div><\/figcaption><\/figure><div class=\"fg-loader\"><\/div><\/div><div class=\"fg-item fg-type-image fg-idle\"><figure class=\"fg-item-inner\"><a href=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/NGBS-organizers-MS-JL-2018-1-scaled.jpeg\" data-caption-title=\"NGBS organizers MS JL 2018\" data-attachment-id=\"1191\" data-type=\"image\" class=\"fg-thumb\"><span class=\"fg-image-wrap\"><img decoding=\"async\" title=\"NGBS organizers MS JL 2018\" width=\"333\" height=\"200\" class=\"skip-lazy fg-image\" data-src-fg=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/cache\/NGBS-organizers-MS-JL-2018-1-scaled\/2934943733.jpeg\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20width%3D%22333%22%20height%3D%22200%22%20viewBox%3D%220%200%20333%20200%22%3E%3C%2Fsvg%3E\" loading=\"eager\"><\/span><span class=\"fg-image-overlay\"><\/span><\/a><figcaption class=\"fg-caption\"><div class=\"fg-caption-inner\"><div class=\"fg-caption-title\">NGBS organizers MS JL 2018<\/div><\/div><\/figcaption><\/figure><div class=\"fg-loader\"><\/div><\/div><div class=\"fg-item fg-type-image fg-idle\"><figure class=\"fg-item-inner\"><a href=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/NGBS-speakers-and-organizers-v2-2019.jpg\" data-caption-title=\"NGBS speakers and organizers 2019\" data-attachment-id=\"1177\" data-type=\"image\" class=\"fg-thumb\"><span class=\"fg-image-wrap\"><img decoding=\"async\" title=\"NGBS speakers and organizers 2019\" width=\"333\" height=\"200\" class=\"skip-lazy fg-image\" data-src-fg=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/cache\/NGBS-speakers-and-organizers-v2-2019\/4237518151.jpg\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20width%3D%22333%22%20height%3D%22200%22%20viewBox%3D%220%200%20333%20200%22%3E%3C%2Fsvg%3E\" loading=\"eager\"><\/span><span class=\"fg-image-overlay\"><\/span><\/a><figcaption class=\"fg-caption\"><div class=\"fg-caption-inner\"><div class=\"fg-caption-title\">NGBS speakers and organizers 2019<\/div><\/div><\/figcaption><\/figure><div class=\"fg-loader\"><\/div><\/div><div class=\"fg-item fg-type-image fg-idle\"><figure class=\"fg-item-inner\"><a href=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/NGBS-speakers-and-organizers-2019.jpg\" data-caption-title=\"NGBS speakers and organizers 2019\" data-attachment-id=\"1178\" data-type=\"image\" class=\"fg-thumb\"><span class=\"fg-image-wrap\"><img decoding=\"async\" title=\"NGBS speakers and organizers 2019\" width=\"333\" height=\"200\" class=\"skip-lazy fg-image\" data-src-fg=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/cache\/NGBS-speakers-and-organizers-2019\/2362618781.jpg\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20width%3D%22333%22%20height%3D%22200%22%20viewBox%3D%220%200%20333%20200%22%3E%3C%2Fsvg%3E\" loading=\"eager\"><\/span><span class=\"fg-image-overlay\"><\/span><\/a><figcaption class=\"fg-caption\"><div class=\"fg-caption-inner\"><div class=\"fg-caption-title\">NGBS speakers and organizers 2019<\/div><\/div><\/figcaption><\/figure><div class=\"fg-loader\"><\/div><\/div><div class=\"fg-item fg-type-image fg-idle\"><figure class=\"fg-item-inner\"><a href=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/Next-Gen-Biophys-Symposium-2020.png\" data-caption-title=\"NGBS speakers 2020\" data-attachment-id=\"1200\" data-type=\"image\" class=\"fg-thumb\"><span class=\"fg-image-wrap\"><img decoding=\"async\" title=\"NGBS speakers 2020\" width=\"333\" height=\"200\" class=\"skip-lazy fg-image\" data-src-fg=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/cache\/Next-Gen-Biophys-Symposium-2020\/2379366160.png\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20width%3D%22333%22%20height%3D%22200%22%20viewBox%3D%220%200%20333%20200%22%3E%3C%2Fsvg%3E\" loading=\"eager\"><\/span><span class=\"fg-image-overlay\"><\/span><\/a><figcaption class=\"fg-caption\"><div class=\"fg-caption-inner\"><div class=\"fg-caption-title\">NGBS speakers 2020<\/div><\/div><\/figcaption><\/figure><div class=\"fg-loader\"><\/div><\/div><div class=\"fg-item fg-type-image fg-idle\"><figure class=\"fg-item-inner\"><a href=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/NGBS-speakers-and-organizers-2022.jpg\" data-caption-title=\"NGBS speakers and organizers 2022\" data-attachment-id=\"1173\" data-type=\"image\" class=\"fg-thumb\"><span class=\"fg-image-wrap\"><img decoding=\"async\" title=\"NGBS speakers and organizers 2022\" width=\"333\" height=\"200\" class=\"skip-lazy fg-image\" data-src-fg=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/cache\/NGBS-speakers-and-organizers-2022\/450006586.jpg\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20width%3D%22333%22%20height%3D%22200%22%20viewBox%3D%220%200%20333%20200%22%3E%3C%2Fsvg%3E\" loading=\"eager\"><\/span><span class=\"fg-image-overlay\"><\/span><\/a><figcaption class=\"fg-caption\"><div class=\"fg-caption-inner\"><div class=\"fg-caption-title\">NGBS speakers and organizers 2022<\/div><\/div><\/figcaption><\/figure><div class=\"fg-loader\"><\/div><\/div><div class=\"fg-item fg-type-image fg-idle\"><figure class=\"fg-item-inner\"><a href=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/NGBS-speakers-and-organizers-2023-1-scaled.jpg\" data-caption-title=\"NGBS speakers and organizers 2023\" data-attachment-id=\"1187\" data-type=\"image\" class=\"fg-thumb\"><span class=\"fg-image-wrap\"><img decoding=\"async\" title=\"NGBS speakers and organizers 2023\" width=\"333\" height=\"200\" class=\"skip-lazy fg-image\" data-src-fg=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/cache\/NGBS-speakers-and-organizers-2023-1-scaled\/1496837001.jpg\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20width%3D%22333%22%20height%3D%22200%22%20viewBox%3D%220%200%20333%20200%22%3E%3C%2Fsvg%3E\" loading=\"eager\"><\/span><span class=\"fg-image-overlay\"><\/span><\/a><figcaption class=\"fg-caption\"><div class=\"fg-caption-inner\"><div class=\"fg-caption-title\">NGBS speakers and organizers 2023<\/div><\/div><\/figcaption><\/figure><div class=\"fg-loader\"><\/div><\/div><div class=\"fg-item fg-type-image fg-idle\"><figure class=\"fg-item-inner\"><a href=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/NGBS-attendees-2023-1-scaled.jpg\" data-caption-title=\"NGBS attendees 2023\" data-attachment-id=\"1192\" data-type=\"image\" class=\"fg-thumb\"><span class=\"fg-image-wrap\"><img decoding=\"async\" title=\"NGBS attendees 2023\" width=\"333\" height=\"200\" class=\"skip-lazy fg-image\" data-src-fg=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/cache\/NGBS-attendees-2023-1-scaled\/2565636105.jpg\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20width%3D%22333%22%20height%3D%22200%22%20viewBox%3D%220%200%20333%20200%22%3E%3C%2Fsvg%3E\" loading=\"eager\"><\/span><span class=\"fg-image-overlay\"><\/span><\/a><figcaption class=\"fg-caption\"><div class=\"fg-caption-inner\"><div class=\"fg-caption-title\">NGBS attendees 2023<\/div><\/div><\/figcaption><\/figure><div class=\"fg-loader\"><\/div><\/div><div class=\"fg-item fg-type-image fg-idle\"><figure class=\"fg-item-inner\"><a href=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/NGBS-speakers-and-organizers-2024.jpg\" data-caption-title=\"NGBS speakers and organizers 2024\" data-attachment-id=\"1207\" data-type=\"image\" class=\"fg-thumb\"><span class=\"fg-image-wrap\"><img decoding=\"async\" title=\"NGBS speakers and organizers 2024\" width=\"333\" height=\"200\" class=\"skip-lazy fg-image\" data-src-fg=\"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-content\/uploads\/sites\/3\/cache\/NGBS-speakers-and-organizers-2024\/2332222516.jpg\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20width%3D%22333%22%20height%3D%22200%22%20viewBox%3D%220%200%20333%20200%22%3E%3C%2Fsvg%3E\" loading=\"eager\"><\/span><span class=\"fg-image-overlay\"><\/span><\/a><figcaption class=\"fg-caption\"><div class=\"fg-caption-inner\"><div class=\"fg-caption-title\">NGBS speakers and organizers 2024<\/div><\/div><\/figcaption><\/figure><div class=\"fg-loader\"><\/div><\/div><\/div>\n<style type=\"text\/css\">#foogallery-gallery-1206 .fg-item-inner {\r\nborder: none;\r\npadding: none;\r\n}\r\n#foogallery-gallery-1206 .fg-caption {\r\nbackground: linear-gradient(0deg,#000000b3,#0000004d 70%,#0000)\r\n}<\/style><\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>NextGen 2025 <\/summary>\n<p>09:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Registration and Coffee<\/p>\n\n\n\n<p>09:25&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Welcome and Introduction<\/strong> <\/p>\n\n\n\n<p><strong><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Session I \u2013 Cryo-electron microscopy and tomography<\/strong><br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Chair: &nbsp;Taiana Maia de Oliveira Co-Chair: &nbsp;Stephen McLaughlin<\/p>\n\n\n\n<p>09:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Kelly Nguyen<\/strong>, MRC Laboratory of Molecular Biology, UK:<br>&nbsp;<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>Structural mechanism of LINE-1 \u2013 The reverse transcriptase that has written ~30% of our genome<\/em><\/p>\n\n\n\n<p>10:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Xiaodong Zhang<\/strong>, The Francis Crick Institute, London, UK:<br>&nbsp;<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>Mechanism of DNA opening by molecular motor during transcription initiation<\/em><\/p>\n\n\n\n<p>10:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Karl-Peter Hopfer<\/strong>, Gene Centre, LMU, Munich, Germany:<br>&nbsp;<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>The Mre11-Rad50-Nbs1 complex: molecular gating and clustering in the repair of DNA double-strand breaks<\/em><\/p>\n\n\n\n<p>11:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Coffee Break<\/p>\n\n\n\n<p><strong><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Session II \u2013 NMR and Dynamics<\/strong><br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Chair: &nbsp;Maria Flocco Co-Chair: Chris Batters<\/p>\n\n\n\n<p>11:30\u00a0\u00a0\u00a0\u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <strong>John Christodolou<\/strong>, UCL, London, UK:<br><em><strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/strong>Protein folding on the ribosome<\/em><br><\/p>\n\n\n\n<p>12:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Flemming Hansen<\/strong>, UCL, London, UK:<br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>Transforming NMR spectroscopy with Artificial Intelligence<\/em><\/p>\n\n\n\n<p>12:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Paola Turano,<\/strong> Magnetic Resonance Center, University of Florence, Italy:<br><em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Understanding the cellular effects of metallodrugs via untargeted NMR<\/em><\/p>\n\n\n\n<p>13:00&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Lunch Break<\/p>\n\n\n\n<p><strong><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Session III \u2013 New Methodologies<\/strong><br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Chair: &nbsp;Andrea Gohlke Co-Chair: &nbsp;Chris Batters<\/p>\n\n\n\n<p>14:00&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>James Manton,<\/strong> MRC Laboratory of Molecular Biology,UK:<br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>Multispectral live-cell imaging<\/em><\/p>\n\n\n\n<p>14:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>John van Noort<\/strong>, Leiden University, Netherlands:<br><em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>How DNA Sequence Shapes Chromatin Architecture: Single-Molecule Insights<\/em><\/p>\n\n\n\n<p>15:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Sabrina Leslie, <\/strong>UCB Vancouver, Canada:<br><em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Single-particle and single-cell microscopy advance the biophysical characterization, understanding, and optimization of next-generation genomic medicines.<\/em><\/p>\n\n\n\n<p>15.30&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Coffee Break<\/p>\n\n\n\n<p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Session IV \u2013 Single Molecule Techniques<\/strong><br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Chair: &nbsp;Chris Batters Co-Chair: &nbsp;Stephen McLaughlin<\/p>\n\n\n\n<p>16:00\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0 <strong>Christian Kaiser<\/strong>, Utrecht University, Utrecht, Netherlands:<br><em><strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/strong>Single-Molecule Dissection of CAG Repeat RNA Folding<strong>\u00a0\u00a0\u00a0 <\/strong><\/em><\/p>\n\n\n\n<p>16:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Dina Grohmann, <\/strong>University of Regensberg, Regensburg, Germany:<br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>Dissecting transcription initiation using DNA Origami-based single-molecule force spectrometry<\/em><\/p>\n\n\n\n<p>17:00&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Break<\/p>\n\n\n\n<p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Keynote Lecture<\/strong><br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Chair: &nbsp;David Rueda Co-Chair: &nbsp;Maria Flocco<\/p>\n\n\n\n<p>17:10&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Cees Dekker, <\/strong>Delft University of Technology, Delft, Netherlands:<br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>Nanotechnology for single-molecule biology:  from chromosome motors to protein sequencing to building a synthetic cell.<\/em><\/p>\n\n\n\n<p>18:10&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;  &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Closing Remarks by Jan L\u00f6we, <\/strong>Director, MRC Laboratory of Molecular Biology,UK.<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>NextGen 2024<\/summary>\n<p>09:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Registration and Coffee<\/p>\n\n\n\n<p>09:25&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Welcome and Introduction<\/strong> <strong>by Sir Gregory Winter,<\/strong><br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Laboratory of Molecular Biology, MRC,<strong> <\/strong>UK.<\/p>\n\n\n\n<p><strong><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Session I \u2013 Cryo-electron microscopy and tomography<\/strong><br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Chair: &nbsp;Maria Flocco&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Co-Chair: &nbsp;Stephen McLaughlin<\/p>\n\n\n\n<p>09:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Prof. Peijun Zhang<\/strong>, University of Oxford, UK:<br>&nbsp;<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>In situ structural virology: from virus infection to vaccine.<\/em><\/p>\n\n\n\n<p>10:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Prof. James \u2018Jim\u2019 Naismith<\/strong>, University of Oxford, UK:<br>&nbsp;<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>Structure inside the cell; atomic pathology.<\/em><\/p>\n\n\n\n<p>10:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Dr Alessandro Costa, <\/strong>The Francis Crick Institute, London, UK:<br>&nbsp;<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>Activation of a eukaryotic origin of replication visualised by cryo-EM.<\/em><\/p>\n\n\n\n<p>11:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Coffee Break<\/p>\n\n\n\n<p><strong><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Session II \u2013 Single Molecule Applications Sponsored by LUMICKS<\/strong><br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Chair: &nbsp;David Rueda&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Co-Chair: Chris Batters<\/p>\n\n\n\n<p>11:30&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Prof. Ben van Houten, <\/strong>University of Pittsburg, USA:<br><em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>A new single molecule approach to study DNA repair protein dynamics:<br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>seeing is believing.<\/em><\/p>\n\n\n\n<p>12:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Prof. Beat Fierz, <\/strong>Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne, Switzerland:<br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>Imaging real-time single-molecule dynamics in genome regulation.<\/em><\/p>\n\n\n\n<p>12:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Prof. Ben Schuler, <\/strong>University of Zurich, Switzerland:<br><em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Single-molecule dynamics and interactions of disordered proteins:&nbsp; from<br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>disordered&nbsp;complexes to phase separation.<\/em><\/p>\n\n\n\n<p>13:00&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Lunch Break<\/p>\n\n\n\n<p><strong><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Session III \u2013 New Methodologies I Sponsored by BRUKER<\/strong><br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Chair: &nbsp;Geoff Holdgate&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Co-Chair: &nbsp;Chris Johnson<\/p>\n\n\n\n<p>14:00&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Dr Helena Knowles,<\/strong> University of Cambridge, UK:<br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>Diamond quantum sensors for probing living systems.<\/em><\/p>\n\n\n\n<p>14:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Prof. Ruth Cameron,<\/strong> University of Cambridge, UK:<br><em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Ice templating for tissue culture applications.<\/em><\/p>\n\n\n\n<p>15:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Assoc. Prof. Julia Kamenz,<\/strong> University of Groningen, Netherlands:<br><em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Visualizing the cell cycle clock using novel single fluorophore biosensors.<\/em><\/p>\n\n\n\n<p>15.30&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Coffee Break<\/p>\n\n\n\n<p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Session IV \u2013 New Methodologies II<\/strong><br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Chair: &nbsp;Stephen McLaughlin&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Co-Chair: &nbsp;Geoff Holdgate<\/p>\n\n\n\n<p>16:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Assoc. Prof. Arjen Jakobi<\/strong>, Kavli Institute of Nanoscience, Delft, Netherlands:<br><em><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Prospects of nanofluidic cavities for cryo-EM sample preparation and 4D<br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>structural&nbsp;biology.<\/em><\/p>\n\n\n\n<p>16:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Dr Barbora \u0160pa\u010dkov\u00e1<\/strong>, Institute of Physics, Prague, Czech Republic:<br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><em>Quantitative label-free imaging at the single molecule level.<\/em><\/p>\n\n\n\n<p>17:00&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Break<\/p>\n\n\n\n<p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Keynote Lecture<\/strong><br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Chair: &nbsp;David Rueda&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Co-Chair: &nbsp;Maria Flocco<\/p>\n\n\n\n<p>17:10&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Prof. Stefan Hell, <\/strong>Max Planck Institute for Multidisciplinary Sciences, G\u00f6ttingen<br><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>and Max Planck Institute for Medical Research, Heidelberg, Germany:<br><strong><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong><\/strong><em>MINFLUX nanoscopy and related matters.<\/em><\/p>\n\n\n\n<p>18:10&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;  &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Closing Remarks by Jan L\u00f6we, <\/strong>Director, MRC Laboratory of Molecular Biology,UK.<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>NextGen 2023<\/summary>\n<p>9:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Registration &amp; Coffee&nbsp;<\/p>\n\n\n\n<p>9:25&nbsp;&nbsp;&nbsp;&nbsp; David Barford: MRC Laboratory of Molecular Biology<\/p>\n\n\n\n<p><em>Welcome and Introduction<\/em><\/p>\n\n\n\n<p><strong>Session I \u2013 Nanocages and Molecular Assemblies<\/strong><strong>&nbsp;<\/strong>&nbsp;<\/p>\n\n\n\n<p>Chair:&nbsp;&nbsp;Chris Johnson, Co-Chair: Stephen McLaughlin<\/p>\n\n\n\n<p>9:30&nbsp;&nbsp;&nbsp;&nbsp;<strong>Jonathan Heddle<\/strong>, University of Durham, UK:<\/p>\n\n\n\n<p><em>Understanding and building nanomachines from biological molecules<\/em><\/p>\n\n\n\n<p>10:00&nbsp;&nbsp;<strong>Lorna Dougan<\/strong>, University of Leeds, UK:<\/p>\n\n\n\n<p><em>Engineering living hydrogels: from folded proteins to functional protein networks<\/em><\/p>\n\n\n\n<p>10:30&nbsp;&nbsp;<strong>Hendrik Dietz<\/strong> Technical University Munich, Germany:<\/p>\n\n\n\n<p><em>Virus Traps and Other Molecular Machines of the Future<\/em><\/p>\n\n\n\n<p>11:00&nbsp;&nbsp;&nbsp; Coffee Break&nbsp;<\/p>\n\n\n\n<p><strong>Session II \u2013 Imaging Across Scales<\/strong>&nbsp;<\/p>\n\n\n\n<p>Chair:&nbsp;Maria Flocco,&nbsp; Co-Chair: Chris Johnson<\/p>\n\n\n\n<p>11:30&nbsp;&nbsp;<strong>Sonja Hess<\/strong>, AstraZeneca, USA:<\/p>\n\n\n\n<p><em>Integrated Analysis<\/em><em> of N-Glycoproteomic and Global Proteomic of Human High-grade Glioblastoma Reveals Distinct Disease Signatures with Potential Clinical Implications<\/em><\/p>\n\n\n\n<p>12:00&nbsp;&nbsp;<strong>Radu Aricescu<\/strong>, MRC Laboratory of Molecular Biology, UK:<\/p>\n\n\n\n<p><em>One needs more structural tools to solve complex biological puzzles<\/em><\/p>\n\n\n\n<p>12:30&nbsp;&nbsp;<strong>Clemens Kaminski<\/strong>, University of Cambridge, UK:<\/p>\n\n\n\n<p><em>Dynamic imaging of organelle dynamics with optical <\/em><em>super resolution<\/em><em>&nbsp;<\/em><em><\/em><\/p>\n\n\n\n<p>1:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Lunch Break&nbsp;<\/p>\n\n\n\n<p><strong>Session III \u2013 Single Molecule Applications<\/strong><\/p>\n\n\n\n<p>Chair: Chris Batters,&nbsp;&nbsp; Co-Chair: Geoff Holdgate<\/p>\n\n\n\n<p>2:00&nbsp;&nbsp;&nbsp;&nbsp;<strong>Kasia Tych<\/strong>, University of Groningen, Netherlands:<\/p>\n\n\n\n<p><em>Using single-molecule optical tweezers to<\/em><em> study transmembrane proteins \u2013 an unfolding story<\/em><\/p>\n\n\n\n<p>2:30&nbsp;&nbsp;&nbsp;&nbsp;<strong>Sebastian Deindl<\/strong>, Uppsala University, Sweden:<\/p>\n\n\n\n<p><em>Illuminating the regulation of gene expression at the single-molecule level<\/em><\/p>\n\n\n\n<p>3:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Coffee Break&nbsp;<\/p>\n\n\n\n<p><strong>Session IV \u2013 Nucleic Acid Chemistry and Dynamics<\/strong>&nbsp;<\/p>\n\n\n\n<p>Chair:&nbsp;Geoff Holdgate,&nbsp; Co-Chair: Chris Batters<\/p>\n\n\n\n<p>3:30&nbsp;&nbsp;&nbsp;&nbsp;<strong>Andres Ramos<\/strong>, Institute of Structural and Molecular Biology, UCL, UK:<\/p>\n\n\n\n<p><em>mRNA modification &#8211; from bench to neuron<\/em><em><\/em><\/p>\n\n\n\n<p>4:00&nbsp;&nbsp;&nbsp;&nbsp;<strong>Marina Kuimova<\/strong>, Imperial College London, UK:<\/p>\n\n\n\n<p><em>Mapping microscopic viscosity and temperature using molecular rotors<\/em><em><\/em><\/p>\n\n\n\n<p>4:30&nbsp;&nbsp;&nbsp;&nbsp;<strong>Amanda Hargrove<\/strong>, Duke University, USA:<\/p>\n\n\n\n<p><em>Modulating the conformation and function of disease-relevant RNA with small molecules<\/em><\/p>\n\n\n\n<p><strong>5.00<\/strong><strong> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/strong>Break&nbsp;<\/p>\n\n\n\n<p><strong>Keynote Lecture<\/strong><strong>&nbsp;&nbsp;&nbsp;<\/strong><\/p>\n\n\n\n<p>Chair: Maria Flocco,&nbsp; Co-Chair: Stephen McLaughlin<\/p>\n\n\n\n<p>5:10&nbsp;&nbsp;&nbsp;&nbsp;<strong>Matthias Mann<\/strong>, Max-Planck Institute of Biochemistry, Germany:<\/p>\n\n\n\n<p><em>Technological advances in MS-Based proteomics: Deep Visual and Single Cell Proteomics for precision medicine<\/em><\/p>\n\n\n\n<p>6.10&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Jan Lowe<\/strong>, Laboratory of Molecular Biology, MRC, UK<\/p>\n\n\n\n<p><em>Closing remarks<\/em><\/p>\n\n\n\n<p>6:15&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;Drinks Reception&nbsp;<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>NextGen 2022<\/summary>\n<div id=\"target-programme-content\" class=\"collapseomatic_content\">\n\n\n\n<p>9:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Registration &amp; Coffee&nbsp;<\/p>\n\n\n\n<p>9:25&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Welcome and Introduction by <strong>Richard Henderson,&nbsp;<\/strong>Laboratory of Molecular Biology, MRC, UK<\/p>\n\n\n\n<p class=\"has-medium-font-size\"><strong>Session I \u2013 RNA Dynamics&nbsp;<\/strong>&nbsp;<\/p>\n\n\n\n<p>Chair:&nbsp;&nbsp;Maria Flocco,   Co-Chair: Stephen McLaughlin<\/p>\n\n\n\n<p style=\"font-size:18px\">9:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Fr\u00e9d\u00e9ric Allain<\/strong>, ETH, Zurich, Switzerland:<\/p>\n\n\n\n<p style=\"font-size:18px\"><strong><em>FUS phase separation, RNA binding and aging as studied by NMR spectroscopy<\/em><\/strong><\/p>\n\n\n\n<p style=\"font-size:18px\">10:00&nbsp;&nbsp;&nbsp; <strong>David Lilley<\/strong>, University of Dundee, UK:<\/p>\n\n\n\n<p style=\"font-size:18px\">&nbsp;<strong><em>The extent of RNA catalysis \u2013 are there any limits ?<\/em><\/strong><\/p>\n\n\n\n<p style=\"font-size:18px\">10:30&nbsp;&nbsp;&nbsp; <strong>Katya Petzold<\/strong>, Karolinska Institute, Sweden:<\/p>\n\n\n\n<p style=\"font-size:18px\"><strong><em>RNA structural changes and their biological impact by NMR<\/em><\/strong><\/p>\n\n\n\n<p>11:00&nbsp;&nbsp;&nbsp; Coffee Break&nbsp;<\/p>\n\n\n\n<p class=\"has-medium-font-size\"><strong>Session II \u2013 Imaging Across <\/strong><strong>Scales<\/strong>&nbsp;<\/p>\n\n\n\n<p>Chair:&nbsp;Geoff Holdgate,&nbsp; Co-Chair: Chris Johnson<\/p>\n\n\n\n<p style=\"font-size:18px\">11:30&nbsp;&nbsp;&nbsp; <strong>Andreas Frutiger<\/strong>, Lino Biotech, Zurich, Switzerland:<\/p>\n\n\n\n<p style=\"font-size:18px\"><strong><em>Label-free interaction analysis in complex samples \u2013 focal Molography enables novel applications in bioprocessing, drug discovery and diagnostics<\/em><\/strong><\/p>\n\n\n\n<p style=\"font-size:18px\">12:00&nbsp;&nbsp;&nbsp; <strong>Tanmay <\/strong><strong>Bharat<\/strong>, Laboratory of Molecular Biology, MRC, UK:<\/p>\n\n\n\n<p style=\"font-size:18px\"> <strong><em>Understanding physiological processes in bacterial cells using cryo-EM<\/em><\/strong><\/p>\n\n\n\n<p style=\"font-size:18px\">12:30&nbsp;&nbsp;&nbsp; <strong>Jorge Bernardino de la <\/strong><strong>Serna<\/strong>, Imperial College London, UK:<\/p>\n\n\n\n<p style=\"font-size:18px\">&nbsp;<em><strong>Imaging Cholesterol and its enriched domains spatiotemporally across scales<\/strong><\/em><\/p>\n\n\n\n<p>1:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Lunch Break&nbsp;<\/p>\n\n\n\n<p class=\"has-medium-font-size\"><strong>Session III \u2013 Single Molecule Applications<\/strong><\/p>\n\n\n\n<p>Chair: David Rueda,&nbsp;&nbsp; Co-Chair: Geoff Holdgate<\/p>\n\n\n\n<p style=\"font-size:18px\">2:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Nynke Dekker<\/strong>, Delft University of Technology, Netherlands:<\/p>\n\n\n\n<p style=\"font-size:18px\"><strong><em>Dynamic motion during loading and activation of the yeast replisome<\/em><\/strong><\/p>\n\n\n\n<p style=\"font-size:18px\">2:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Alice Pyne<\/strong>, University of Shefield, UK:<\/p>\n\n\n\n<p style=\"font-size:18px\"><em><strong>Uncovering the invisible complexities of the genome using atomic force microscopy<\/strong><\/em><\/p>\n\n\n\n<p style=\"font-size:18px\">3:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Ashley <\/strong><strong>Nord<\/strong>, CNRS, Montpellier, France:<\/p>\n\n\n\n<p style=\"font-size:18px\"><strong>&nbsp;<em>Single cell electrical characterization in bacteria<\/em><\/strong><\/p>\n\n\n\n<p>3:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Coffee Break&nbsp;<\/p>\n\n\n\n<p class=\"has-medium-font-size\"><strong>Session IV \u2013 Computational approaches and Structure <\/strong><strong>Prediction<\/strong>&nbsp;<\/p>\n\n\n\n<p>Chair:&nbsp;Chris Johnson,&nbsp; Co-Chair: Maria Flocco<\/p>\n\n\n\n<p style=\"font-size:18px\">4:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>John <\/strong><strong>Jumper<\/strong>, DeepMind, London, UK:<\/p>\n\n\n\n<p style=\"font-size:18px\"><strong><em>AlphaFold and its implications for understanding biology<\/em><\/strong><\/p>\n\n\n\n<p style=\"font-size:18px\">4:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Giulia Palermo<\/strong>, University of California Riverside, USA:<\/p>\n\n\n\n<p style=\"font-size:18px\"><strong><em>Dynamics and Mechanism of CRISPR-Cas9 through the Lens of Computational Methods<\/em><\/strong><\/p>\n\n\n\n<p style=\"font-size:18px\">5:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Rhiju <\/strong><strong>Das<\/strong>, Stanford University, USA:<\/p>\n\n\n\n<p style=\"font-size:18px\"><strong><em>RNA modeling and design<\/em><\/strong><\/p>\n\n\n\n<p><strong>5.30 &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/strong>Break&nbsp;<\/p>\n\n\n\n<p class=\"has-medium-font-size\"><strong>Keynote Lecture&nbsp;&nbsp;&nbsp;<\/strong><\/p>\n\n\n\n<p>Chair: Stephen McLaughlin,&nbsp; Co-Chair: David Rueda<\/p>\n\n\n\n<p style=\"font-size:18px\">5:40&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>David Baker<\/strong>, University of Washington, USA:<\/p>\n\n\n\n<p style=\"font-size:18px\">&nbsp;<strong><em>Protein design using deep learning<\/em><\/strong><\/p>\n\n\n\n<p>6.40&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Closing Remarks by<strong> Jason Chin<\/strong>, Laboratory of Molecular Biology, MRC, UK<\/p>\n\n\n\n<p>6:45&nbsp;&nbsp;&nbsp;&nbsp; Drinks Reception&nbsp;<\/p>\n\n\n\n<\/div>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>NextGen 2021<\/summary>\n<div id=\"target-programme-content\" class=\"collapseomatic_content\">\n\n\n\n<p>10:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Welcome\/Introduction by <strong>Prof. Jonathan Weber<\/strong>, Dean of the Faculty of Medicine, Imperial College London, UK<\/p>\n\n\n\n<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<strong>Session I \u2013 DNA Repair<\/strong>&nbsp;<\/p>\n\n\n\n<p>Chair:&nbsp;Stephen McLaughlin&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Co-Chair: Chris Johnson<\/p>\n\n\n\n<p>10:10&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<strong>Simon Boulton<\/strong>, The Francis Crick Institute, UK:&nbsp;<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mechanics of Homologous recombination at a single molecule level<\/em><\/p>\n\n\n\n<p>10:40&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<strong>Lori Passmore<\/strong>, Laboratory of Molecular Biology, MRC, UK:<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Insights into DNA crosslink repair through an integrated structural biology approach&nbsp;<\/em><\/p>\n\n\n\n<p>11:10&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<strong>Taiana Maia De Oliveira<\/strong>,&nbsp; AstraZeneca, UK:<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Cryo-EM reveals structural insights on DNA Damage Repair<\/em><\/p>\n\n\n\n<p>11:40&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Coffee Break<\/p>\n\n\n\n<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Session II \u2013 &nbsp;Epigenetics<\/strong><\/p>\n\n\n\n<p>Chair:&nbsp;Maria Flocco&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Co-Chair: David Rueda<\/p>\n\n\n\n<p>11:55&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<strong>Petra Hajkova<\/strong>, London Institute of Medical Sciences, MRC, UK:&nbsp;<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The stability and dynamics of DNA modifications in vivo<\/em><\/p>\n\n\n\n<p>12:25<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Roseana Collepardo<\/strong>, University of Cambridge, UK:<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Liquid-like chromatin organization from multiscale modelling<\/em><\/p>\n\n\n\n<p>12:55&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Lunch Break &nbsp;<\/p>\n\n\n\n<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<strong>Session III \u2013 Imaging Across Scales<\/strong><\/p>\n\n\n\n<p>Chair:&nbsp;Chris Johnson&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Co-Chair:Maria Flocco<\/p>\n\n\n\n<p>13:30<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Hasan Yardimci,<\/strong> The Francis Crick Institute, UK<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Visualising chromatin replication one molecule at a time<\/em><\/p>\n\n\n\n<p>14:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<strong>Beatrice Dyring-Andersen<\/strong>, University of Copenhagen, Denmark:<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mass spectrometry in clinical dermatology<\/em><\/p>\n\n\n\n<p>14:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<strong>Sabrina Leslie<\/strong>, University of British Columbia, Canada:<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Single-molecule insights for drug discovery and development: the next level of resolution<\/em><\/p>\n\n\n\n<p>15:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Coffee Break<\/p>\n\n\n\n<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<strong>Session IV \u2013High-throughput Biophysics<\/strong>&nbsp;<\/p>\n\n\n\n<p>Chair:&nbsp;Geoff Holdgate&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Co-Chair:Chris Johnson<\/p>\n\n\n\n<p>15:15<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Philipp Holliger<\/strong>,&nbsp;Laboratory of Molecular Biology, MRC, UK:<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; High-throughput screening of protein and nucleic acid function<\/em><\/p>\n\n\n\n<p>15:45<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Chirlmin Joo<\/strong>, TU Delft, Netherlands:&nbsp;<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Towards Genome-wide Single-molecule Studies<\/em><\/p>\n\n\n\n<p>16:15<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;William Greenleaf<\/strong>, Stanford University, US:<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Understanding the physical genome in health and disease&nbsp;<\/em><\/p>\n\n\n\n<p>16:45&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Coffee Break&nbsp;<\/p>\n\n\n\n<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<strong>Keynote Lecture<\/strong>&nbsp;<\/p>\n\n\n\n<p>Chair:&nbsp;David Rueda&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Co-Chair:Stephen McLaughlin<\/p>\n\n\n\n<p>17:00<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Patrick Cramer<\/strong>, Max Planck Institute, Germany:&nbsp;<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Towards a mechanistic understanding of genome regulation<\/em><\/p>\n\n\n\n<p>18:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<strong>Close of Meeting<\/strong>&nbsp;<strong>by Jan Lowe,<\/strong>&nbsp;Director of the LMB.<\/p>\n\n\n\n<\/div>\n\n\n\n<p><\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>NextGen 2020<\/summary>\n<div id=\"target-programme-content\" class=\"collapseomatic_content\">\n\n\n\n<p>All timings are local UK time on October 7th 2020<\/p>\n\n\n\n<p>11.00-11.10:&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Welcome and opening remarks<\/strong><\/p>\n\n\n\n<p>Sir Mene Pangalos, EVP Biopharmaceuticals R&amp;D, AstraZeneca.<\/p>\n\n\n\n<p>11.10-12.25:&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Session I:&nbsp; Imaging Across Scales<\/strong><\/p>\n\n\n\n<p>Chair: Stephen McLaughlin, LMB.&nbsp; Co-Chair: Christopher Johnson, LMB<\/p>\n\n\n\n<p>11.10-11.35:&nbsp; Andrew Carter.&nbsp; MRC Laboratory of Molecular Biology, UK.<\/p>\n\n\n\n<p><strong>Shulin: a novel factor packaging axonemal outer dynein arms for ciliary targeting<\/strong><\/p>\n\n\n\n<p>11.35-12.00:&nbsp; Julia Mahamid.&nbsp; EMBL Heidelberg, Germany.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<p><strong>Molecular view into cellular functions by in-cell cryo-electron tomography<\/strong><\/p>\n\n\n\n<p>12.00-12.25&nbsp; Richard Goodwin.&nbsp; Drug Discovery AstraZeneca, UK.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<p><strong>Integrated molecular imaging\u2013technologies with the power to offer a new view on the tissue microenvironment and map the efficacy and safety of new therapies<\/strong><\/p>\n\n\n\n<p>12.25-13.00:&nbsp;&nbsp; Break 35 minutes<\/p>\n\n\n\n<p>13.00-14.15:&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Session II:&nbsp; Theory and Simulation<\/strong><\/p>\n\n\n\n<p>Chair: Geoff Holdgate, AstraZeneca.&nbsp; Co-Chair: Christopher Johnson, LMB<\/p>\n\n\n\n<p>13.00-13.25:&nbsp; Martin Depken.&nbsp; TU Delft, Netherlands.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<p><strong>Using mechanistic modelling to improve off-target activity predictions and elucidate the physical basis of SpCas9 fidelity<\/strong><\/p>\n\n\n\n<p>13.25-13.50:&nbsp; Philip Biggin.&nbsp; Dept. Biochemistry, University of Oxford, UK.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<p><strong>Computational biophysics of trafficking receptors<\/strong><\/p>\n\n\n\n<p>13.50-14.15:&nbsp; Andres Cisneros, University of North Texas, US<\/p>\n\n\n\n<p><strong>Leveraging Computational Approaches to Uncover and Characterize Cancer-Associated Missense Mutations<\/strong><\/p>\n\n\n\n<p>14.15-14.30:&nbsp;&nbsp;&nbsp; Break 15 minutes<\/p>\n\n\n\n<p>14.30-15.45:&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;<strong>Session III:&nbsp; Biological Phase Separation<\/strong><\/p>\n\n\n\n<p>Chair: Maria Flocco, AstraZeneca.&nbsp; Co-Chair: David Rueda, Imperial College, London<\/p>\n\n\n\n<p>14.30-14.55:&nbsp; Evan Sprujit.&nbsp; Radboud University, Netherlands.<\/p>\n\n\n\n<p><strong>Understanding biological phase transitions with minimal peptide-based models<\/strong><\/p>\n\n\n\n<p>14.55-15.20:&nbsp; Priya Banerjee.&nbsp; Dept. Physics. University at Buffalo, USA.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<p><strong>Emergent structure and dynamics of protein-RNA condensates<\/strong><\/p>\n\n\n\n<p>15.20-15.45:&nbsp; Stephanie Weber.&nbsp; Dept. Biology, McGill University, Canada.<\/p>\n\n\n\n<p><strong>No membrane, no problem: condensing bacterial organelles<\/strong><\/p>\n\n\n\n<p>15.45-16.00:&nbsp;&nbsp;&nbsp; Break 15 minutes<\/p>\n\n\n\n<p>16.00-17.00&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Keynote Lecture<\/strong><\/p>\n\n\n\n<p>Chair: David Rueda, Imperial College, London.&nbsp; Co-Chair: Maria Flocco, AstraZeneca<\/p>\n\n\n\n<p>Prof. Petra Schwille.&nbsp; Director, Max Plank Institute for Biochemistry, Martinsried, Germany<\/p>\n\n\n\n<p><strong>Is there a minimal set of functions for life?<\/strong><\/p>\n\n\n\n<p>17.00-17.10&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Closing Remarks<\/strong> Jan L\u00f6we, Director, MRC Laboratory of Molecular Biology&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<\/div>\n\n\n\n<p><\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>NextGen 2019<\/summary>\n<p>9:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Registration &amp; Coffee<\/strong><\/p>\n\n\n\n<p>9:25 &nbsp;&nbsp;&nbsp;&nbsp; <strong>Welcome\/Introduction by Mike Snowden, Head of Discovery Sciences, AstraZeneca<\/strong><\/p>\n\n\n\n<p><strong>Session I &#8211; New and Emerging Technologies <\/strong>&nbsp;&nbsp;Chair: Christopher Johnson. MRC-LMB, Cambridge<\/p>\n\n\n\n<p>9:30 &nbsp;&nbsp;&nbsp;&nbsp; Christopher Russo.&nbsp; MRC LMB, Cambridge.<\/p>\n\n\n\n<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Understanding and approaching some physical limits in CryoEM<\/strong><\/p>\n\n\n\n<p>10:00&nbsp; &nbsp; Paul French.&nbsp; Imperial College London.<\/p>\n\n\n\n<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Multidimensional fluorescence imaging<\/strong><\/p>\n\n\n\n<p>10:30 &nbsp;&nbsp; Madhavi Krishnan<strong>.&nbsp; <\/strong>Chemistry, Oxford.<\/p>\n\n\n\n<p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Bringing electrostatics to light: Electrometry probes a new dimension at the molecular scale<\/strong><\/p>\n\n\n\n<p>11:00&nbsp;&nbsp;&nbsp; <strong>Coffee Break<\/strong><\/p>\n\n\n\n<p><strong>Session II \u2013 Molecular Conformation and Architecture<\/strong> Chair: Stephen McLaughlin. MRC LMB, Cambridge<\/p>\n\n\n\n<p>11:30&nbsp; &nbsp;&nbsp;Alireza Mashaghi-Tabari.&nbsp; Leiden University, Netherlands<\/p>\n\n\n\n<p><strong>Dissecting cellular protein folding processes using single-molecule force spectroscopy<\/strong>&nbsp;<\/p>\n\n\n\n<p>12:00 &nbsp;&nbsp; Peter St George-Hyslop, Cambridge Institute for Medical Reasearch<\/p>\n\n\n\n<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Physiological and Pathological Biological Condensates in Neurons<\/strong><\/p>\n\n\n\n<p>12:30&nbsp;&nbsp;&nbsp; Wanda Kukulski. MRC LMB, Cambridge.<\/p>\n\n\n\n<p><strong>Using correlative microscopy and electron cryo-tomography to visualise the molecular architecture of cellular membranes<\/strong><\/p>\n\n\n\n<p>1:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Lunch Break<\/strong><\/p>\n\n\n\n<p><strong>Session III &#8211; Single Molecule Applications<\/strong> Chair: David Rueda. Imperial College London<\/p>\n\n\n\n<p>2:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Stephan Uphoff. Biochemistry, Oxford.<\/p>\n\n\n\n<p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Single-molecule imaging of bacterial DNA repair and mutagenesis<\/strong><\/p>\n\n\n\n<p>2:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Anders Gunnarsson. AstraZeneca<\/p>\n\n\n\n<p><strong>Small-molecule drug discovery enabled through dynamic and static single-molecule detection approaches<\/strong><\/p>\n\n\n\n<p>3:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Christian Speck. Imperial College London.<\/p>\n\n\n\n<p><em>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <\/em><strong>Structural and functional analysis of eukaryotic DNA replication<\/strong><\/p>\n\n\n\n<p>3:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Coffee Break<\/strong><\/p>\n\n\n\n<p><strong>Session IV \u2013 Molecular Mass Matters<\/strong>. &nbsp;Chair: Maria Flocco, Astra Zeneca<\/p>\n\n\n\n<p>4:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Justin Benesch. Chemistry, Oxford.<\/p>\n\n\n\n<p><strong>Weighing the evidence for protein structure and dynamic<\/strong><strong>s<\/strong><\/p>\n\n\n\n<p>4:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Jonathan Wingfield.&nbsp;&nbsp; AstraZeneca<\/p>\n\n\n\n<p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mass spectrometry at the speed of sound: the application of acoustics for sample loading<\/strong><\/p>\n\n\n\n<p><strong>Keynote Lecture<\/strong><\/p>\n\n\n\n<p>5:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Prof Dame Carol Robinson. Chemistry, Oxford.<\/p>\n\n\n\n<p><strong>From peripheral proteins to membrane motors \u2013 mass spectrometry comes of age&nbsp; <\/strong><\/p>\n\n\n\n<p>5:45&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Close of Meeting by Jan Lowe, Director of the MRC LMB<\/strong><\/p>\n\n\n\n<p>6:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Drinks Reception<\/strong><\/p>\n\n\n\n<p><\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>NextGen 2018<\/summary>\n<p>9:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Registration &amp; Coffee<\/p>\n\n\n\n<p>9:25 &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Welcome\/Introduction by Mike Snowden<\/strong>, Head of&nbsp;&nbsp;&nbsp;&nbsp; Discovery Sciences, AstraZeneca<\/p>\n\n\n\n<p><strong>Session I &#8211; Nucleic Acid Enzymes and Machines<\/strong><\/p>\n\n\n\n<p>Chair: David Rueda, Imperial College, London<\/p>\n\n\n\n<p>9:30 &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Ben Taylor<\/strong>, AstraZeneca, Cambridge:<\/p>\n\n\n\n<p><em>DNA bubbles induce Cas9 off-target cutting<\/em><\/p>\n\n\n\n<p>10:00 &nbsp;&nbsp;&nbsp; <strong>Mark Dillingham<\/strong>, School of Biochemistry, Bristol:<\/p>\n\n\n\n<p><em>The dynamic architecture of ParB-DNA complexes and their role in bacterial chromosome segregation<\/em><\/p>\n\n\n\n<p>10:30 &nbsp;&nbsp;&nbsp; <strong>Achillefs Kapanidis<\/strong>, Dept of Physics, Oxford:<\/p>\n\n\n\n<p><em>Discovering transcription mechanisms via single-molecule imaging in vitro and in vivo<\/em><\/p>\n\n\n\n<p>11:00&nbsp;&nbsp;&nbsp;&nbsp; Coffee Break<\/p>\n\n\n\n<p><strong>Session II &#8211; Protein Conformation<\/strong><\/p>\n\n\n\n<p>Chair: Stephen McLaughlin, LMB, Cambridge<\/p>\n\n\n\n<p>11:30 &nbsp;&nbsp;&nbsp; <strong>Perdita Barran<\/strong>, School of Chemistry, Manchester:<\/p>\n\n\n\n<p><em>Using Mass Spectrometry to study IDPs \u2013 The perfect tool to examine self-solvation and fuzzy complexes<\/em><\/p>\n\n\n\n<p>12:00 &nbsp;&nbsp;&nbsp; <strong>Sergi Garcia-Manyes<\/strong>, Kings College, London:<\/p>\n\n\n\n<p><em>The mechanical stability of proteins regulates their translocation rate into the cell nucleus<\/em><\/p>\n\n\n\n<p>12:30&nbsp;&nbsp;&nbsp;&nbsp; <strong>Justin Benesch<\/strong>, Dept of Chemistry, Oxford:<\/p>\n\n\n\n<p><em>Weighing the evidence for the assembly and dynamics of proteins<\/em><\/p>\n\n\n\n<p>1:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Lunch Break<\/p>\n\n\n\n<p><strong>Session III &#8211; New Technologies<\/strong><\/p>\n\n\n\n<p>Chair: Geoff Holdgate, Astra Zeneca<\/p>\n\n\n\n<p>2:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Mark Leake<\/strong>, Dept of Physics, York:<\/p>\n\n\n\n<p><em>Illuminating the black box of DNA-Protein Interactions<\/em><\/p>\n\n\n\n<p>2:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Philipp Kukura<\/strong>, Dept of Chemistry, Oxford:<\/p>\n\n\n\n<p><em>Weighing single molecules with light<\/em><\/p>\n\n\n\n<p>3:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Steven Lee<\/strong>, Dept of Chemistry, Cambridge: <em>Multidimensional Super-resolution Imaging<\/em><\/p>\n\n\n\n<p>3:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Coffee Break<\/p>\n\n\n\n<p><strong>Session IV &#8211; Recognition and Signalling<\/strong><\/p>\n\n\n\n<p>Chair: Maria Flocco, Astra Zeneca<\/p>\n\n\n\n<p>4:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Marisa Martin-Fernandez<\/strong>, STFC Central Laser Facility, Harwell: &nbsp;<\/p>\n\n\n\n<p><em>The architecture of EGFR\u2019s basal complexes reveals autoinhibition mechanisms in dimers and oligomers<\/em><\/p>\n\n\n\n<p>4:30&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Isabel Llorente-Garcia<\/strong>, Dept Physics and Astronomy, UCL, London:<\/p>\n\n\n\n<p><em>Investigating molecular interactions relevant to virus entry in living cells via optical tweezers force spectroscopy and light-sheet fluorescence microscopy<\/em><\/p>\n\n\n\n<p><strong>Keynote Lecture<\/strong><\/p>\n\n\n\n<p>5:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Richard Henderson<\/strong>, LMB, Cambridge:&nbsp;&nbsp;<\/p>\n\n\n\n<p><em>Single Particle cryoEM technology<\/em><\/p>\n\n\n\n<p>5:45&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Close of Meeting by Jan Lowe, Director of the MRC-LMB<\/p>\n\n\n\n<p>6:00&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Drinks Reception<\/p>\n\n\n\n<p><\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>NextGen 2017<\/summary>\n<p>9.00 \u2013 9.15 Arrive<\/p>\n\n\n\n<p>9.15 \u2013 9.30 Welcome \/ Introduction by Mike Snowden, Head of Discovery Sciences, AstraZeneca<\/p>\n\n\n\n<p>Session I, Chairperson: Geoff Holdgate<\/p>\n\n\n\n<p>9.30 \u2013 Bart Hoogenboom, London Centre for Nanotechnology, University College London: <strong>Probing individual biomolecules and biomolecular assemblies with better than super-resolution<\/strong><\/p>\n\n\n\n<p>10.00 \u2013 Stefan Geschwindner, AstraZeneca, Gothenburg, Sweden: <strong>Seeing drugs in action:<\/strong> <strong>From molecular ensembles to single molecules with TIRF microscopy<\/strong><\/p>\n\n\n\n<p>10.30 \u2013 Robert Henderson, Dept. Pharmacology, University of Cambridge:&nbsp;<strong>Molecules and movement: Studies using fast-scan atomic force microscopy<\/strong><\/p>\n\n\n\n<p>11.00 \u2013 11.30 Coffee<\/p>\n\n\n\n<p>Session II, Chairperson: Stephen McLaughlin<\/p>\n\n\n\n<p>11.30 \u2013 Charlotte Dodson, National Heart &amp; Lung Institute, Imperial College London: <strong>Dynamic equilibrium of Aurora-A kinase activation loop revealed by single molecule spectroscopy<\/strong><\/p>\n\n\n\n<p>12.00 \u2013 Luca Pellegrini, Dept. Biochemistry, University of Cambridge: <strong>Biophysical studies of the meiotic protein SYCP3<\/strong><\/p>\n\n\n\n<p>12.30 \u2013 David Rueda, Dept. Medicine, Imperial College London: <strong>Watching protein-nucleic acid interactions with single molecule resolution<\/strong><\/p>\n\n\n\n<p>1.00 \u2013 2.00 \u2013 Lunch<\/p>\n\n\n\n<p>Session III, Chairperson: Maria M. Flocco<\/p>\n\n\n\n<p>2.00 \u2013 Roger Williams&nbsp; LMB, Cambridge: <strong>Using hydrogen\/deuterium exchange mass spectrometry to understand regulation of cellular signalling<\/strong><\/p>\n\n\n\n<p>2.30 \u2013 Justin Molloy, Crick Institute, London: <strong>Use of optically-based single molecule techniques to study molecular machines<\/strong><\/p>\n\n\n\n<p>3.00 \u2013 David Klenerman, Dept. Chemistry, University of Cambridge: <strong>Single molecule studies of neurodegeneration<\/strong><\/p>\n\n\n\n<p>3.30 \u2013 4.00 Coffee<\/p>\n\n\n\n<p>Session IV, Chairperson: Chris Johnson<\/p>\n\n\n\n<p>4.00 \u2013 Bruce Carrington, UCB Pharma, Slough: <strong>Structural and biophysical techniques to investigate protein conformations in PPI drug discovery<\/strong><\/p>\n\n\n\n<p>4.30 \u2013 Sonia Antoranz Contera, Dept. of Physics, University of Oxford<strong>:&nbsp; AFM and beyond: Forces and mechanics to image, quantify and steer biological function from single molecules to cells and living tissues<\/strong><\/p>\n\n\n\n<p>5.00 \u2013 Emmanuel Derivery, LMB, Cambridge: <strong>Polarized endosome dynamics by spindle asymmetry during asymmetric cell division<\/strong><\/p>\n\n\n\n<p>5.30 \u2013 Close of Meeting by Sir Hugh Pelham, Director of the MRC-LMB<\/p>\n\n\n\n<p>Drinks Reception<\/p>\n\n\n\n<p><\/p>\n<\/details>\n\n\n<\/details>\n<p><!-- \/wp:post-content --><\/p>","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"class_list":{"0":"post-295","1":"page","2":"type-page","3":"status-publish","5":"entry"},"featured_image_src":null,"featured_image_src_square":null,"_links":{"self":[{"href":"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-json\/wp\/v2\/pages\/295","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-json\/wp\/v2\/comments?post=295"}],"version-history":[{"count":58,"href":"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-json\/wp\/v2\/pages\/295\/revisions"}],"predecessor-version":[{"id":1271,"href":"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-json\/wp\/v2\/pages\/295\/revisions\/1271"}],"wp:attachment":[{"href":"https:\/\/www3.mrc-lmb.cam.ac.uk\/sites\/nextgen\/wp-json\/wp\/v2\/media?parent=295"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}