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Next Generation Biophysics

Programme : Next Generation Biophysics 2025

09:00Registration and Coffee
09:25Welcome and Introduction

Session I – Cryo-electron microscopy and tomography
Chair: Taiana Maia de Oliveira Co-Chair: Stephen McLaughlin
09.30Kelly Nguyen, MRC Laboratory of Molecular Biology, UK:
TBA
10:00Xiaodong Zhang, The Francis Crick Institute, London, UK:
Mechanism of DNA opening by molecular motor during transcription initiation
10:30Karl-Peter Hopfer, Gene Centre, LMU, Munich, Germany:
TBA
11:00Coffee Break

Session II – NMR and Dynamics
Chair:  Maria Flocco Co-Chair: Chris Batters
11:30John Christodolou, UCL, London, UK:
TBA
12:00Flemming Hansen, UCL, London, UK:
Transforming NMR spectroscopy with Artificial Intelligence
12:30Paola Turano, Magnetic Resonance Center, University of Florence, Italy:
Understanding the cellular effects of metallodrugs via untargeted NMR
13:00Lunch Break

Session III – New Methodologies
Chair: Andrea Gohlke Co-Chair: Chris Batters
14:00James Manton, MRC Laboratory of Molecular Biology,UK:
TBA
14:30John van Noort, Leiden University, Netherlands:
How DNA Sequence Shapes Chromatin Architecture: Single-Molecule Insights
15:00Sabrina Leslie, UCB Vancouver, Canada:
Single-particle and single-cell microscopy advance the biophysical characterization, understanding, and optimization of next-generation genomic medicines
15:30Coffee Break

Session IV – Single Molecule Techniques
Chair:  Chris Batters Co-Chair:  Stephen McLaughlin
16:00Christian Kaiser, Utrecht University, Utrecht, Netherlands:
Single-Molecule Dissection of CAG Repeat RNA Folding
16:30Dina Grohmann, University of Regensberg, Regensburg, Germany:
TBA
17:00Break

Keynote Lecture
Chair:  David Rueda Co-Chair:  Maria Flocco
17:10Cees Dekker, Delft University of Technology, Delft, Netherlands:
Nanotechnology for single-molecule biology:  from chromosome motors to protein sequencing to building a synthetic cell.
18:10Closing Remarks by Jan Löwe, Director, MRC Laboratory of Molecular Biology,UK.