9:00 Registration & Coffee
9:25 Sir Gregory Winter
Welcome and Introduction
Session I – Cryo-electron microscopy and tomography
Chair: Maria Flocco, Co-Chair: Stephen McLaughlin
9:30 Prof. Peijun Zhang, University of Oxford, UK:
In situ structural virology: from virus infection to vaccine.
10:00 Prof. James ‘Jim’ Naismith, University of Oxford, UK:
Structure inside the cell; atomic pathology.
10:30 Dr. Alessandro Costa, The Francis Crick Institute, London, UK:
Activation of a eukaryotic origin of replication visualised by cryo-EM.
11:00 Coffee Break
Session II – Single Molecule Applications
Chair: David Rueda, Co-Chair: Chris Batters
11:30 Prof. Ben van Houten, University of Pittsburgh Cancer Institute, USA:
A new single molecule approach to study DNA repair protein dynamics: seeing is believing.
12:00 Prof. Beat Fierz, Ecole polytechnique fédérale de Lausanne, Switzerland:
Imaging real-time single-molecule dynamics in genome regulation.
12:30 Prof. Ben Schuler, University of Zurich, Switzerland:
Single-molecule dynamics and interactions of disordered proteins: From disordered complexes to phase separation.
1:00 Lunch Break
Session III – New Methodologies I
Chair: Geoff Holdgate, Co-Chair: Chris Johnson
2:00 Dr. Helena Knowles, University of Cambridge, UK:
Diamond quantum sensors for probing living systems
2:30 Prof. Ruth Cameron, University of Cambridge, UK:
Ice templating for tissue culture applications
3:00 Ass. Prof. Julia Kamenz, University of Groningen, Netherlands:
Visualizing the cell cycle clock using novel single fluorophore biosensors.
3:30 Coffee Break
Session IV – New Methodologies II
Chair: Stephen McLaughlin, Co-Chair: Geoff Holdgate
4:00 Ass. Prof. Arjen Jakobi, Kavli Institute of Nanoscience, Delft, Netherlands:
Prospects of nanofluidic cavities for cryo-EM sample preparation and 4D structural biology
4:30 Dr. Barbora Špačková , Institute of Physics, Prague, Czech Republic:
Quantitative Label-Free Imaging at the Single Molecule Level
5.00 Break
Keynote Lecture
Chair: David Rueda, Co-Chair: Maria Flocco
5:10 Prof. Stefan Hell
Max Planck Institute for Multidisciplinary Sciences, Göttingen & Max Planck Institute for Medical Research, Heidelberg, Germany:
MINFLUX nanoscopy and related matters
6.10 Jan Lowe, Director, MRC Laboratory of Molecular Biology, UK
Closing remarks
6:15 Drinks Reception